It can also occur iatrogenically from prolonged nitroprusside infusion. ![]() While it is fortunately a rare cause for presentation to emergency departments, cyanide is one of the most rapidly fatal toxins known, so diagnosis and treatment must be expeditious.Ĭyanide toxicity can occur from a range of different exposures, including smoke inhalation from burning plastics in house fires, intentional ingestions in suicide attempts and industrial exposures among individuals working in the jewelry, photography, metallurgy or textile industries. ![]() Now there is a newer, safer agent that converts the mitochondrial toxin, cyanide, into the benign chemical cyanocobalamin, or vitamin B12. Cyanide toxicity can be quickly fatal, but there is a simple, safe treatment that can reverse its toxic effects.įor many years, cyanide toxicity was treated with multi-component cyanide antidote kits.
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